Package: AiES Type: Package Title: Axon Integrity Evaluation System for Microscopy Images Version: 1.0.0 Authors@R: c( person("Shinji", "Tokunaga", email = "tokunaga@ncnp.go.jp", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-8398-3054")), person("Masabumi", "Funakoshi", email = "funakoshi@ncnp.go.jp", role = "ctb"), person("Toshiyuki", "Araki", email = "taraki@ncnp.go.jp", role = "ctb", comment = c(ORCID = "0000-0003-3625-2042")), person("National Center of Neurology and Psychiatry", role = "cph") ) Description: Provides tools for the quantitative analysis of axon integrity in phase-contrast microscopy images. 'AiES' (Axon integrity Evaluation System) implements image pre-processing, adaptive thresholding, feature extraction, and support vector machine-based classification to compute indices such as the Axon Integrity Index (AII) and Degeneration Index (DI). Two built-in models are provided, and classifiers can be re-trained on user data. The package is designed for reproducible and automated analysis in neuroscience research. License: BSD_3_clause + file LICENSE Copyright: 2025 National Center of Neurology and Psychiatry Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 URL: https://github.com/BreezyCave/AiES BugReports: https://github.com/BreezyCave/AiES/issues Depends: R (>= 3.6.0) Imports: EBImage, e1071, stats, fs, utils, data.table, rstudioapi, tiff Suggests: knitr, rmarkdown, tcltk, svDialogs VignetteBuilder: knitr Config/pak/sysreqs: cmake libfftw3-dev make libjpeg-dev libpng-dev libtiff-dev libuv1-dev Repository: https://breezycave.r-universe.dev Date/Publication: 2026-11-02 06:14:15 UTC RemoteUrl: https://github.com/breezycave/aies RemoteRef: HEAD RemoteSha: 2f9c9d0160fb673a57f2c915a5b53cb012634490 NeedsCompilation: no Packaged: 2026-11-02 07:54:59 UTC; root Author: Shinji Tokunaga [aut, cre] (ORCID: ), Masabumi Funakoshi [ctb], Toshiyuki Araki [ctb] (ORCID: ), National Center of Neurology and Psychiatry [cph] Maintainer: Shinji Tokunaga